Assessment of hydroalcoholic extract of Thymus Vulgaris on neurogenic and inflammatory pain in mice

Background and Objective: The side effects of anti-nociception chemical drugs caused notice to medical plants. This study was performed to investigate the effects of hydroalcoholic extract of Thymus vulgaris (TV) on neurogenic and inflammatory pain in formalin test in mice. Methods: 40 male albino m...

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Veröffentlicht in:Majallah-i Dānishgāh-i ʻUlūm-i Pizishkī̄-i Bābul 2005-04, Vol.7 (2), p.24-29
Hauptverfasser: AA Taherian, A Rashidi Pour, M Arefi, A Vafaei, M Emami Abarghoei, H Sadeghi, M Jarrahi, H Miladi Gorji
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Sprache:eng
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Zusammenfassung:Background and Objective: The side effects of anti-nociception chemical drugs caused notice to medical plants. This study was performed to investigate the effects of hydroalcoholic extract of Thymus vulgaris (TV) on neurogenic and inflammatory pain in formalin test in mice. Methods: 40 male albino mice (20-30 gr) were used. TV (100, 500 mg/kg) as extract and saline were injected 30 mine before formalin test. Indexes for evaluation were duration of licking and foot elevation for assessment of acute pain (5 min) and chronic pain (15-40 min) after injection of formalin 5% (25 µl) in paw. Findings: Results indicated that TV has analgesic effect in both doses (P
ISSN:1561-4107
2251-7170