Forty-year-old diabetic lady with tightness in lower limbs

Forty-year-old diabetic lady with tightness in lower limbs

[...] the main clinical findings were stiffness in the limbs and trunk and painful spasms triggered with sudden stimuli or movement. {Figure 3} Her anti-GAD antibody was negative.\n [8] Antibodies Up to 65% of the patients may have antibodies against the two isoforms of GAD, GAD-65 and GAD-67. Becau...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Annals of the Indian Academy of Neurology 2012-01, Vol.15 (1), p.15-18
Hauptverfasser: Khade, Snehaldatta S, Deshmukh, Shrikant S, Dhonde, Pramod V, Khadilkar, Satish V
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Autoimmune diseases
Baldness
Care and treatment
Development and progression
Diabetes
Diagnosis
Grand Round
Molecular weight
Occupational therapy
Sleep
Stiff-person syndrome
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:[...] the main clinical findings were stiffness in the limbs and trunk and painful spasms triggered with sudden stimuli or movement. {Figure 3} Her anti-GAD antibody was negative.\n [8] Antibodies Up to 65% of the patients may have antibodies against the two isoforms of GAD, GAD-65 and GAD-67. Because GAD is also present in the pancreatic cells, serum specimens from patients with the Stiff Person syndrome who are positive for anti-GAD antibodies also stain the β cells of the pancreas.
ISSN:0972-2327
1998-3549
DOI:10.4103/0972-2327.93269