Distinctive features and prognostic utility of neutrophil in severe patients with Klebsiella pneumoniae infection

Neutrophil plays a pivotal role in the management of infection. Delineate the clinical characteristics and prognostic utility of neutrophil in severe patients with infection are crucial for clinical management and prognostic assessment. patients with different infection sites were enrolled from Medi...

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Veröffentlicht in:Frontiers in cellular and infection microbiology 2024-09, Vol.14, p.1406168
Hauptverfasser: Du, Chunjing, Lu, Ming, Zheng, Jiajia, Liu, Chao, Yang, Ping, Yi, Juan, Zhu, Liuluan, Shen, Ning
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Sprache:eng
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Zusammenfassung:Neutrophil plays a pivotal role in the management of infection. Delineate the clinical characteristics and prognostic utility of neutrophil in severe patients with infection are crucial for clinical management and prognostic assessment. patients with different infection sites were enrolled from Medical Information Mart for Intensive Care IV and eICU Collaborative Research Database. Temporal variations of neutrophil counts within 30 days of clinical onset were examined using locally weighted scatterplot smoothing curves. Logistic regression analysis was performed to assess the relationship between neutrophil counts and hospital mortality. A total of 1,705 patients caused by were included in the study. The non-survivor group exhibited a comparatively older age and a higher proportion of infections originating from respiratory and bloodstream sources compared to the survivor group (38.4% vs 21.1%, p
ISSN:2235-2988
2235-2988
DOI:10.3389/fcimb.2024.1406168