Genome characterization of bile-isolated Shewanella algae ACCC

has been recognized as an emerging human pathogen. However, not much is known about the mechanism of its pathogenesis and its adaptation to a special niche such as the hepatobiliary tract. In this study, we isolated the ACCC strain from human bile and performed whole genome sequencing. ACCC consists...

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Veröffentlicht in:Gut pathogens 2018-09, Vol.10 (1), p.38-6, Article 38
Hauptverfasser: Tseng, Shu-Ying, Tung, Kwong-Chung, Cheng, Jan-Fang, Lee, Yi-Hsuan, Wu, Zong-Yen, Hong, Yu-Kai, Chen, Shi-Yu, Huang, Yao-Ting, Liu, Po-Yu
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Sprache:eng
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Zusammenfassung:has been recognized as an emerging human pathogen. However, not much is known about the mechanism of its pathogenesis and its adaptation to a special niche such as the hepatobiliary tract. In this study, we isolated the ACCC strain from human bile and performed whole genome sequencing. ACCC consists of a circular 4,743,354-bp chromosome with a GC content of 53.08%, within 4080 protein coding sequences. The genome of strain ACCC contains a number of candidate genes which have been reported to be associated with bile adaption, including , , , and regulon. Our results highlight the association of with a rare disease profile. Further studies are needed to shed light on the evolution of pathogenesis and the niche adaptation of .
ISSN:1757-4749
1757-4749
DOI:10.1186/s13099-018-0267-4