Genome characterization of bile-isolated Shewanella algae ACCC
has been recognized as an emerging human pathogen. However, not much is known about the mechanism of its pathogenesis and its adaptation to a special niche such as the hepatobiliary tract. In this study, we isolated the ACCC strain from human bile and performed whole genome sequencing. ACCC consists...
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Veröffentlicht in: | Gut pathogens 2018-09, Vol.10 (1), p.38-6, Article 38 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | has been recognized as an emerging human pathogen. However, not much is known about the mechanism of its pathogenesis and its adaptation to a special niche such as the hepatobiliary tract.
In this study, we isolated the
ACCC strain from human bile and performed whole genome sequencing.
ACCC consists of a circular 4,743,354-bp chromosome with a GC content of 53.08%, within 4080 protein coding sequences. The genome of strain ACCC contains a number of candidate genes which have been reported to be associated with bile adaption, including
,
,
,
and
regulon.
Our results highlight the association of
with a rare disease profile. Further studies are needed to shed light on the evolution of pathogenesis and the niche adaptation of
. |
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ISSN: | 1757-4749 1757-4749 |
DOI: | 10.1186/s13099-018-0267-4 |