Gastric cancer and trastuzumab: first biologic therapy in gastric cancer

Gastric cancer and trastuzumab: first biologic therapy in gastric cancer

Gastric cancer remains difficult to cure and has a poor overall prognosis. Chemotherapy and multimodality therapy has shown some benefit in the treatment of gastric cancer. Current therapies for gastric cancer have their limitations; thus, we are in need of newer treatment options including targeted...

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Veröffentlicht in:Therapeutic Advances in Medical Oncology 2013-03, Vol.5 (2), p.143-151
Hauptverfasser: Gunturu, Krishna S., Woo, Yanghee, Beaubier, Nike, Remotti, Helen E., Saif, M. Wasif
Format: Artikel
Sprache:eng
Schlagworte:
Cancer therapies
Chemotherapy
Epidermal growth factor
ErbB-2 protein
Gastric cancer
Immunotherapy
Monoclonal antibodies
Reviews
Targeted cancer therapy
Trastuzumab
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Beschreibung
Zusammenfassung:Gastric cancer remains difficult to cure and has a poor overall prognosis. Chemotherapy and multimodality therapy has shown some benefit in the treatment of gastric cancer. Current therapies for gastric cancer have their limitations; thus, we are in need of newer treatment options including targeted therapies. Here, we review the biologic therapy with trastuzumab in human epidermal growth factor receptor 2 (HER2)+ gastric cancer.
ISSN:1758-8340
1758-8359
1758-8359
DOI:10.1177/1758834012469429