Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015

During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Emerging infectious diseases 2016-02, Vol.22 (2), p.327-330
Hauptverfasser:	Seong, Moon-Woo, Kim, So Yeon, Corman, Victor Max, Kim, Taek Soo, Cho, Sung Im, Kim, Man Jin, Lee, Seung Jun, Lee, Jee-Soo, Seo, Soo Hyun, Ahn, Ji Soo, Yu, Byeong Su, Park, Nare, Oh, Myoung-don, Park, Wan Beom, Lee, Ji Yeon, Kim, Gayeon, Joh, Joon Sung, Jeong, Ina, Kim, Eui Chong, Drosten, Christian, Park, Sung Sup
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis coronavirus Coronavirus Infections - epidemiology Coronavirus Infections - history Coronavirus Infections - transmission Coronavirus Infections - virology Disease Outbreaks Dispatch Evolution Evolution, Molecular Genetic Variation genome sequencing Genome, Viral Genomics History, 21st Century Humans Male MERS-CoV Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 Middle East respiratory syndrome Middle East Respiratory Syndrome Coronavirus - genetics Middle East Respiratory Syndrome Coronavirus - isolation & purification phylogenetic analysis Phylogeny Republic of Korea - epidemiology viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2202.151700