Investigation of the Circadian Rhythm of Blood Pressure in Patients with Metabolic Syndrome and its Association with Metabolic Parameters

Background and Objectives: Many diseases, such as metabolic syndrome, cancer and cardiovascular diseases, are associated with circadian rhythm. This study was performed with the aim of assessing blood pressure in individuals with metabolic syndrome and association of metabolic parameters of this syndrome with blood pressure rhythm. Methods: This cross-sectional study was conducted on patients referred to the clinics of Shahid Beheshti and Vali-asr hospitals in Qom city. Among them, 109 patients were selected using census method from April 2014 to completion of the sample size. Data collection was performed using a demographic characteristics checklist and results of 24-hour blood pressure monitoring. data were analyzed using t-test and chi square. Results: In this study, the age range of patients was between 30 to 85 years old with the mean of 53.08±13.82, which 65.1% (71 subjects) were female and 34.9% (38 subjects) were male. Among the woman, 76.1% (54 subjects) and among the men, 71.1% (27 subjects) had non-dipper blood pressure (p=0.569). The mean of fasting blood sugar in non-dipper group was 108.39±32.66 and in dipper group was 104.35±18.74 (p=0.537). The prevalence of non-dipper hypertension in patients with diabetes (87%) was significantly higher than non-diabetic patients (65.1%) (p=0.015). Conclusion: The findings of this study showed that distribution of age, sex, and metabolic syndrome parameters, such as blood glucose, obesity (BMI) and plasma lipids in the non-dipper group, were not significantly different from the dipper group, but the prevalence of non-dipper hypertension in diabetic patients was higher.