Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature

With the rapid development of various coronavirus disease 2019 (COVID-19) vaccines in a bid to counter and contain the COVID-19 pandemic, unusual and uncommon side effects of COVID-19 vaccination have been increasingly reported in the literature. Ipsilateral lymphadenopathy is a fairly common side e...

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Veröffentlicht in:Vaccines (Basel) 2021-11, Vol.9 (11), p.1251
Hauptverfasser: Tan, Hui Min, Hue, Susan Swee-Shan, Wee, Aileen, See, Kay Choong
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Sprache:eng
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Zusammenfassung:With the rapid development of various coronavirus disease 2019 (COVID-19) vaccines in a bid to counter and contain the COVID-19 pandemic, unusual and uncommon side effects of COVID-19 vaccination have been increasingly reported in the literature. Ipsilateral lymphadenopathy is a fairly common side effect of vaccination of any kind, with its etiology most commonly related to reactive lymphadenopathy. However, Kikuchi–Fujimoto Disease (KFD) or necrotizing histiocytic lymphadenitis is rarely observed post-vaccination, with only one other case of KFD post COVID-19 vaccination reported to date. We report two more cases of KFD post COVID-19 vaccination in the Asian population, highlighting the clinical course and salient clinical, radiological and histologic findings. In addition, we provide a literature review of the existing cases of lymphadenopathy post COVID-19 vaccination with cytologic and/or histologic correlation.
ISSN:2076-393X
2076-393X
DOI:10.3390/vaccines9111251