Nanoencapsulation of Eggplant (Solanum melongena L.) Peel Extract in Electrospun Gelatin Nanofiber: Preparation, Characterization, and In Vitro Release

This study describes the preparation and characterization of eggplant peel extract-loaded electrospun gelatin nanofiber and study of its in vitro release. Results obtained by scanning electron microscopy (SEM) and transmission electronic microscopy (TEM) micrograph revealed that eggplant peel extrac...

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Veröffentlicht in:Nanomaterials (Basel, Switzerland) Switzerland), 2022-07, Vol.12 (13), p.2303
Hauptverfasser: Estrella-Osuna, Danya Elizabeth, Tapia-Hernández, José Agustín, Ruíz-Cruz, Saúl, Márquez-Ríos, Enrique, Ornelas-Paz, José de Jesús, Del-Toro-Sánchez, Carmen Lizette, Ocaño-Higuera, Víctor Manuel, Rodríguez-Félix, Francisco, Estrada-Alvarado, María Isabel, Cira-Chávez, Luis Alberto
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Sprache:eng
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Zusammenfassung:This study describes the preparation and characterization of eggplant peel extract-loaded electrospun gelatin nanofiber and study of its in vitro release. Results obtained by scanning electron microscopy (SEM) and transmission electronic microscopy (TEM) micrograph revealed that eggplant peel extract-loaded electrospun gelatin nanofiber is in nanometric range with an average diameter 606.7 ± 184.5 and 643.6 ± 186.7 nm for 20 and 33.3 mg mL−1 of extract addition, respectively. Moreover, the incorporation of extract improved morphology by being smooth, homogeneous, and without account formation compared to nanofibers without extract (control). Fourier transform-infrared (FT-IR) spectra indicated that interaction exists between electrospun gelatin nanofiber and eggplant peel extract by hydrogen bond interactions, mainly. Electrospun gelatin nanofibers showed encapsulation efficiency greater than 90% of extract and a maximum release of 95 and 80% for the medium at pH 1.5 and 7.5, respectively. Therefore, the electrospinning technique is a good alternative for the conservation of bioactive compounds present in the eggplant peel through electrospun gelatin nanofiber.
ISSN:2079-4991
2079-4991
DOI:10.3390/nano12132303