Mean Platelet Volume in Patients with Subclavian Arterial Stenosis

Objective: Thrombocytes and mean platelet volume (MPV) are related to atherosclerosis. The purpose of the present study was to investigate the relationship between MPV and subclavian arterial stenosis (SAS). Materials and Methods: Patients who were diagnosed with SAS by an angiography performed in the catheter laboratory between September 2010 and September 2015 were included in this study. A control group with similar clinical and demographic characteristics as the patients with SAS in angiographic terms was formed. The MPV and other hemogram values for SAS patients (35 patients) and the patients in the control group (38 patients) were determined retrospectively from the registry system and then compared. Results: The two groups were similar to each other in terms of demographic and clinical characteristics. When the hemogram parameters were compared between the groups, the MPV was detected as being significantly higher in patients with SAS (8.07 ± 1.41 vs 7.19 ± 0.52; p = 0.001). Conclusion: In conclusion, this study was the first to find a higher MPV in patients with SAS. Considering both the effect of platelets on atherosclerosis and their close association with other risk factors, MPV level may be an important factor in pathogenesis of SAS.