Genomic Epidemiology of Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae in Kenya, Uganda, and Jordan

Surveillance of antimicrobial resistance in Kenya, Uganda, and Jordan identified multidrug-resistant high-risk bacterial clones: Escherichia coli sequence types 131, 1193, 69, 167, 10, 648, 410, 405 and Klebsiella pneumoniae sequence types 14, 147, 307, 258. Clones emerging in those countries exhibi...

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Veröffentlicht in:	Emerging infectious diseases 2024-10, Vol.30 (14), p.33-S40
Hauptverfasser:	Byarugaba, Denis K, Osman, Tamer S, Sayyouh, Omar M, Wokorach, Godfrey, Kigen, Collins K, Muturi, James W, Onyonyi, Vanessa N, Said, Mayar M, Nasrat, Salwa A, Gazo, Mahmoud, Erima, Bernard, Alafi, Stephen, Kabatesi, Hope O, Wabwire-Mangen, Fred, Kibuuka, Hannah, Sapre, Anjali P, Bartlett, Katelyn V, Lebreton, Francois, Martin, Melissa J, Mahugu, Evelyn W, Smith, Hunter J, Musila, Lillian A
Format:	Artikel
Sprache:	eng
Schlagworte:	and Anti-Bacterial Agents - pharmacology Antimicrobial agents Antimicrobial resistance bacteria Cloning Drug resistance Drug Resistance, Multiple, Bacterial - genetics E coli Epidemiology Escherichia coli Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - isolation & purification Escherichia coli Infections - epidemiology Escherichia coli Infections - microbiology Genes Genetic diversity Genomes Genomic Epidemiology of Multidrug-Resistant Genomics - methods Health surveillance high-risk clones Hospitals Humans in Kenya, Uganda, and Jordan Jordan - epidemiology Kenya - epidemiology Klebsiella Infections - epidemiology Klebsiella Infections - microbiology Klebsiella pneumoniae Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - genetics Microbial Sensitivity Tests Molecular Epidemiology multidrug resistance Nosocomial infections Pathogens Plasmids Uganda - epidemiology Virulence
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Beschreibung
Zusammenfassung:	Surveillance of antimicrobial resistance in Kenya, Uganda, and Jordan identified multidrug-resistant high-risk bacterial clones: Escherichia coli sequence types 131, 1193, 69, 167, 10, 648, 410, 405 and Klebsiella pneumoniae sequence types 14, 147, 307, 258. Clones emerging in those countries exhibited high resistance mechanism diversity, highlighting a serious threat for multidrug resistance.
ISSN:	1080-6040 1080-6059 1080-6059
DOI:	10.3201/eid3014.240370