Potential predictors for prognosis and postpartum recovery time of acute fatty liver of pregnancy

Acute fatty liver of pregnancy (AFLP) is a potentially lethal condition of pregnant women with a high mortality rate. Potential predictors related to postpartum recovery time and prognostic factors of AFLP are still unclear. This study aimed to evaluate potential predictors for prognosis and postpar...

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Veröffentlicht in:	BMC Pregnancy and Childbirth 2020-10, Vol.20 (1), p.601-601, Article 601
Hauptverfasser:	Chen, Jun, Huang, Ze-Bing, Fan, Xue-Gong, Hu, Xing-Wang, Qi, Min, Liao, Cheng-Jin, Long, Li-Yuan, Huang, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute fatty liver of pregnancy Adult Biopsy Blood Blood Component Transfusion - methods Blood Component Transfusion - statistics & numerical data Factor VIII - administration & dosage Fatty liver Fatty Liver - complications Fatty Liver - mortality Fatty Liver - therapy Female Fetuses Fibrinogen - administration & dosage Gestational age Health aspects Hepatic Encephalopathy - epidemiology Hepatitis Humans Laboratories Liver Liver, Artificial Medical prognosis Mortality Plasma Postpartum Period Postpartum recovery time Potential predictors Pregnancy Pregnancy Complications - mortality Pregnancy Complications - therapy Pregnant women Prognosis Recovery (Medical) Regression analysis Retrospective Studies Risk Assessment - statistics & numerical data Risk Factors Time Factors Ultrasonic imaging Young Adult
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Zusammenfassung:	Acute fatty liver of pregnancy (AFLP) is a potentially lethal condition of pregnant women with a high mortality rate. Potential predictors related to postpartum recovery time and prognostic factors of AFLP are still unclear. This study aimed to evaluate potential predictors for prognosis and postpartum recovery time of AFLP. We retrospectively analyzed the clinical data of 76 AFLP patients in our hospital from 2002 to 2017 and investigated potential predictors using univariate analysis and multivariate logistic regression analysis. Hepatic encephalopathy (HE) was found to be associated with prognosis in AFLP patients (P = 0.005, OR = 26.844). The postpartum recovery time analysis showed that AFLP patients with a age
ISSN:	1471-2393 1471-2393
DOI:	10.1186/s12884-020-03287-y