Micro-elimination of hepatitis C in patients with chronic kidney disease: an Egyptian single-center study

Micro-elimination of hepatitis C in patients with chronic kidney disease: an Egyptian single-center study

Background and aims Micro-elimination of hepatitis C in renal patients is crucial. This study aims to assess the efficacy and safety of directly acting antivirals in chronic kidney disease patients and the effect of treatment on kidney functions. Results This prospective cohort study included 77 chr...

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Veröffentlicht in:The Egyptian journal of internal medicine 2022-12, Vol.34 (1), p.1-10, Article 54
Hauptverfasser: George Michael, Tari, Anwar, Christina A., Ahmed, Ossama A., Sarhan, Iman, Elshazly, Yehia, Shaker, Mohammed K., Eltabbakh, Mohammed, Hashem, Walaa, Tawfic, Safaa R., Kamel, Shimaa Y., Kandil, Doaa M., Naguib, Gina G., Khedr, Abdelrahman, Ghanem, Eman A., Dabbous, Hany, Doss, Wahid, El-Sayed, Manal H.
Format: Artikel
Sprache:eng
Schlagworte:
CKD
DAA
Direct-acting antivirals
HCV
Hepatitis C
Internal Medicine
Medicine
Medicine & Public Health
Micro-elimination
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Zusammenfassung:Background and aims Micro-elimination of hepatitis C in renal patients is crucial. This study aims to assess the efficacy and safety of directly acting antivirals in chronic kidney disease patients and the effect of treatment on kidney functions. Results This prospective cohort study included 77 chronic HCV-infected patients with chronic kidney disease. Patients were consented and treated for 12 weeks with either sofosbuvir and daclatasvir ± ribavirin if glomerular filtration rate was > 30 mL/min per 1.73m 2 or ritonavir-boosted paritaprevir-ombitasvir-ribavirin if it was 
ISSN:1110-7782
2090-9098
DOI:10.1186/s43162-022-00139-3