Performance comparison of different advanced control schemes for glucose level control under disturbing meal

In this work, diabetic glucose concentration level control under disturbing meal has been controlled using two set of advanced controllers. The first set is sliding mode controllers (classical and integral) and the second set is represented by optimal LQR controllers (classical and Min-, ax). Due to their characteristic features of disturbance rejection, both integral sliding mode controller and LQR Minmax controller are dedicated here for comparison. The Bergman minimal mathematical model was used to represent the dynamic behavior of a diabetic patient’s blood glucose concentration to the insulin injection. Simulations based on Matlab/Simulink, were performed to verify the performance of each controller. In spite that Min-max optimal controller gave better disturbance rejection capability than classical optimal controller, classical sliding mode controller could outperform Min-max controller. However, it has been shown that integral sliding mode controller is the best of all in terms of disturbance rejection capability.