Right lower limb apraxia in a patient with left supplementary motor area infarction： intactness of the corticospinal tract confirmed by transcranial magnetic stimulation

We reported a 50-year-old female patient with left supplementary motor area infarction who presented right lower limb apraxia and investigated the possible causes using transcranial magnetic stimulation. The patient was able to walk and climb stairs spontaneously without any assistance at 3 weeks af...

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Veröffentlicht in:	Neural regeneration research 2015-02, Vol.10 (2), p.325-327
Hauptverfasser:	Chang, Min Cheol, Chun, Min Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	acupuncture Alzheimer′s disease amplitude of low-frequency fluctuation amyloid-β Angong Niuhuang sticker antioxidation Apraxia astrocytes astrocytoma autophagy axon growth blood circulation bone marrow mesenchymal stem cells brachial plexus injury brain brain injury brain network brain-derived neurotrophic factor Brodmann area 11 Brodmann area 18 Brodmann area 19 Brodmann area 44 Ca 2 calcilytic calcium-sensing receptor Care and treatment Case studies CD133 cell apoptosis cell proliferation cell transplantation cerebral infarct cerebral ischemia compartment syndrome connectivity contusion corticospinal tract creep cyclosporine A Diagnosis differentiation dopaminergic neurons earthquake edaravone electroacupuncture electrophysiological function feature binding Fisher′s Z transform fluorescent quantitative PCR forepaw function functional magnetic resonance imaging Gait glial fibrillary acidic protein human amniotic epithelial cells Imaging in Neural Regeneration immunodeficiency (BALB/c) mice immunohistochemistry inflammation injection injury intervertebral disc LC3 lower limb apraxia LSUHSC score Medical research mice microRNA-9 microtubule-associated protein middle cerebral artery occlusion module division motor function MPTP MRI nerve decompression nerve regeneration nestin neural progenitor cells neural regeneration neuroblast differentiation neuroelectrophysiology neurogenesis neuroimaging neurological function neurological functions neuron specific enolase neuron-like cells neurons neuroprotection nitromemantine Nogo-A Notch NPS 2143 NSFC grants Oenanthe javanica extract oligodendrocytes Parkinson′s disease Patients penicillin G potassium peripheral nerve injury physiotherapy point application polysaccharide from Spirulina platensis posterior lobe of the cerebellum proliferation rat resting state resting-state functional magnetic resonance imaging Schwann cells spinal cord spinal cord injury stress relaxation Stroke Studies supplementary motor area surgery therapy surgical decompression Taichong (LR3) Taixi (KI3) task state traditional Chinese medicine Transcranial magnetic stimulation tumor necrosis factor α vascular endothelial growth factor viscoelasticity visual stimuli Wallerian degeneration α7-nicotinic acetylcholine receptor 下肢功能障碍患者整性皮质脊髓束经颅磁刺激诱发电位辅助运动区
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Zusammenfassung:	We reported a 50-year-old female patient with left supplementary motor area infarction who presented right lower limb apraxia and investigated the possible causes using transcranial magnetic stimulation. The patient was able to walk and climb stairs spontaneously without any assistance at 3 weeks after onset. However, she was unable to intentionally move her right lower limb although she understood what she supposed to do. The motor evoked potential evoked by transcranial magnetic stimulation from the right lower limb was within the normal range, indicating that the corticospinal tract innervating the right lower limb was uninjured. Thus, we thought that her motor dysfunction was not induced by motor weakness, and confirmed her symptoms as aprax- ia. In addition, these results also suggest that transcranial magnetic stimulation is helpful for diagnosing apraxia.
ISSN:	1673-5374 1876-7958
DOI:	10.4103/1673-5374.152389