Pharmacogenetics in clinical practice

Pharmacogenetics in clinical practice

Pharmacogenetics is a discipline that investigates how genetic variation relates to the drug efficacy and safety. The goal of pharmacogenetics is a personalized treatment, where according to genotype we would be able to prescribe the most effective drug at the most appropriate dose for an individual...

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Veröffentlicht in:Prague medical report 2012, Vol.113 (4), p.251-261
Hauptverfasser: Bakhouche, H, Slanař, O
Format: Artikel
Sprache:eng
Schlagworte:
Humans
Irinotecan
Maraviroc
Opioid analgesics
Personalized medicine
Pharmaceutical Preparations
Pharmacogenetics
Polymorphism
Polymorphism, Genetic
Precision Medicine
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Zusammenfassung:Pharmacogenetics is a discipline that investigates how genetic variation relates to the drug efficacy and safety. The goal of pharmacogenetics is a personalized treatment, where according to genotype we would be able to prescribe the most effective drug at the most appropriate dose for an individual patient. The aim of this review is to summarize pharmacogenetics as a specialization with its own background, research, methods, including barriers and promises for the future.
ISSN:1214-6994
2336-2936
DOI:10.14712/23362936.2015.8