Treatment effects of cumulative cisplatin dose during radiotherapy following induction chemotherapy in nasopharyngeal carcinoma: propensity score analyses

Treatment effects of cumulative cisplatin dose during radiotherapy following induction chemotherapy in nasopharyngeal carcinoma: propensity score analyses

Background: The treatment effects of cumulative cisplatin dose (CCD) during radiotherapy (RT) following induction chemotherapy (IC) have not been determined for patients with locoregionally advanced nasopharyngeal carcinoma (NPC). Methods: A total of 3460 patients with locoregionally advanced NPC wh...

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Veröffentlicht in:Therapeutic advances in medical oncology 2020, Vol.12, p.1758835920937424
Hauptverfasser: Peng, Liang, Chen, Jia-Luo, Zhu, Guang-Li, Huang, Cheng-Long, Li, Jun-Yan, Ma, Jun, Wen, Wei-Ping, Tang, Ling-Long
Format: Artikel
Sprache:eng
Schlagworte:
Chemoradiotherapy
Chemotherapy
Cisplatin
Metastases
Metastasis
Nasopharyngeal carcinoma
Original Research
Radiation therapy
Survival
Throat cancer
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Zusammenfassung:Background: The treatment effects of cumulative cisplatin dose (CCD) during radiotherapy (RT) following induction chemotherapy (IC) have not been determined for patients with locoregionally advanced nasopharyngeal carcinoma (NPC). Methods: A total of 3460 patients with locoregionally advanced NPC who were treated with IC plus cisplatin-based concurrent chemoradiotherapy or RT alone were included in this retrospective study. Three CCD groups (0 mg/m2 ⩽ CCD 
ISSN:1758-8359
1758-8340
1758-8359
DOI:10.1177/1758835920937424