Effects of the cafeteria diet on the salivary glands of trained and sedentary Wistar rats/Efeitos da dieta de cafeteria sobre as glandulas salivares de ratos Wistar sedentarios e treinados

The objective of this work was to study the effect of the aerobic physical training and the cafeteria diet introduced after weaning of Wistar rats and on the morphology of the main salivary glands (parotid, submandibular, sublingual). Male rats after weaning were subjected to the cafeteria diet or the standard rodent chow, and either performed aerobic physical training in a treadmill for 100 days, or did not performed any physical activity. Analyses were done considering the response in body weight, adipose tissues and salivary glands, and the data were submitted to statistical treatment (p < 0.05). The morphological and morphometric analyses of the salivary glands were performed through histological sections stained with hematoxylin and eosin. Despite the normophagic behavior, the rodents fed with the cafeteria diet became obese, with repercussions on parotid gland weight. However, this obesity and/or physical training did not influence the histological organization of the salivary glands. The morphometric analysis of the submandibular glands pointed out a reduction in the levels of serous acinar cells as an effect of the diet and physical training. In conclusion, the parotid and the submandibular glands alter themselves due to the nature and consistency of food present in the cafeteria diet as well as due to the aerobic physical training. Keywords: salivary gland, cafeteria diet, aerobic physical training, obesity. O objetivo deste trabalho foi avaliar as caracteristicas morfologicas das glandulas salivares (parotida, submandibular, sublingual) apresentadas por ratos submetidos a treinamento fisico aerobio e dieta de cafeteria apos o periodo de lactacao. Ratos machos apos a lactacao consumiram dieta de cafeteria ou racao-padrao para roedores e realizaram treinamento fisico aerobio em esteira rolante por µm periodo de 100 dias, ou nao realizaram nenhuma atividade fisica. Foram feitas analises sobre a resposta do peso corporal, dos tecidos adiposos e das glandulas salivares e os dados submetidos a tratamento estatistico (p < 0,05). A analise morfologica e morfometrica das glandulas salivares foi realizada a partir de cortes histologicos corados com Hematoxilina e Eosina. Apesar do comportamento normofagico, os roedores alimentados com dieta de cafeteria apresentaram maior quantidade de gordura corporal, com repercussao sobre o peso da glandula parotida. A analise morfometrica das glandulas submandibulares indicou reducao na proporcao dos acinos serosos com