Gold Nanoparticles Covered Hollow SiO2 Nanocapsules for DOX Delivery and Multiple Antitumor

Gold Nanoparticles Covered Hollow SiO2 Nanocapsules for DOX Delivery and Multiple Antitumor

A chemo and photothermal therapy integrated nanoplatform, DOX-loaded and AuNPs-covered hollow SiO2 nanocapsules (Au-HMSN@DOX), were constructed for enhanced cancer therapy via sequential NIR irradiation. HMSN are used as nanocarriers for drug delivery. AuNPs exhibit an outstanding photothermal effec...

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Bibliographische Detailangaben
Hauptverfasser: Chang, Guanru, Shen, Yuhua, Chun Pei, Long, Chen
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Anticancer properties
Chemotherapy
Drug delivery systems
Gold
Nanoparticles
Near infrared radiation
Silicon dioxide
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Beschreibung
Zusammenfassung:A chemo and photothermal therapy integrated nanoplatform, DOX-loaded and AuNPs-covered hollow SiO2 nanocapsules (Au-HMSN@DOX), were constructed for enhanced cancer therapy via sequential NIR irradiation. HMSN are used as nanocarriers for drug delivery. AuNPs exhibit an outstanding photothermal effect for increasing the local temperature. Compared with HMSN@DOX, the combination of NIR light-triggered photothermal of AuNPs and Chemotherapy of DOX leads to enhanced antitumor effect and reduced side effect.
ISSN:2274-7214
2261-236X
DOI:10.1051/matecconf/20166701013