Impact of needle positioning on ablation success of irreversible electroporation: a unicentric retrospective analysis

Irreversible electroporation (IRE) is an ablation procedure in which cell death is induced by ultrashort electrical pulses. In this unicentric retrospective study we investigated the influence of needle positioning on ablation success. 15 IREs with residual tumor after ablation, detected in the firs...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2020-12, Vol.10 (1), p.21902-21902, Article 21902
Hauptverfasser:	Mathy, René Michael, Tinoush, Parham, da Florencia, Ricardo Daniel, Braun, Alexander, Ghamarnejad, Omid, Radeleff, Boris, Kauczor, Hans-Ulrich, Chang, De-Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/409 692/4020/4021/1607/1604 692/4020/4021/1607/1610/4029 692/699/67/1059 692/699/67/2321 Ablation Aged Carcinoma, Hepatocellular - diagnostic imaging Carcinoma, Hepatocellular - therapy Cell death Electroporation Female Humanities and Social Sciences Humans Liver Neoplasms - diagnostic imaging Liver Neoplasms - therapy Magnetic Resonance Imaging Male Middle Aged multidisciplinary Navigation systems Needles Retrospective Studies Science Science (multidisciplinary) Success Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Irreversible electroporation (IRE) is an ablation procedure in which cell death is induced by ultrashort electrical pulses. In this unicentric retrospective study we investigated the influence of needle positioning on ablation success. 15 IREs with residual tumor after ablation, detected in the first follow-up MRI, were included, and compared with 30 successful ablations. Evaluation of needle geometry revealed significantly higher values for needle divergence (NDiv, 7.0° vs. 3.7°, p = 0.02), tumor-center-to-ablation-center distance (TACD, 11.6 vs. 3.2 mm, p
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-020-78660-0