Predicting the results of surgical treatment of idiopathic macular hole

To determine structural and functional parameters the most informative in predicting the anatomic effect of surgical treatment of idiopathic macular hole (IMH). Using the spectral-domain optical coherence tomography (SD-OCT) we examined 165 patients (173 eyes) before and after surgery for the IMH. Possible prognostic parameters were determined by the ROC-analysis and stepwise discriminant analysis in the study group (111 patients, 118 eyes) and were evaluated retrospectively in a test group (54 patients, 55 eyes). The most informative prognostic indicator was the average thickness of the retina in the foveal zone (AUC 0.935; at a fixed specificity of 95%: sensitivity - 54.5% and a thresh - old value for prediction of unfavorable outcome of the operation -