Impact of sensitization and ABO blood types on the opportunity of deceased-donor kidney transplantation with prolonged waiting time

Impact of sensitization and ABO blood types on the opportunity of deceased-donor kidney transplantation with prolonged waiting time

The waiting time to deceased-donor kidney transplantation (DDKT) is long in Asian countries. We investigated the impact of sensitization and ABO blood type (ABO) on DDKT opportunity using two Korean cohorts: a hospital cohort from two centers and a national database. The impact of panel reactive ant...

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Veröffentlicht in:Scientific reports 2024-02, Vol.14 (1), p.2635-2635, Article 2635
Hauptverfasser: Lee, Jin Hyeog, Koo, Tai Yeon, Lee, Jung Eun, Oh, Kook Hwan, Kim, Beom Seok, Yang, Jaeseok
Format: Artikel
Sprache:eng
Schlagworte:
692/4022
692/499
ABO system
Blood
Blood groups
Humanities and Social Sciences
Kidney transplantation
Kidney transplants
multidisciplinary
Science
Science (multidisciplinary)
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Zusammenfassung:The waiting time to deceased-donor kidney transplantation (DDKT) is long in Asian countries. We investigated the impact of sensitization and ABO blood type (ABO) on DDKT opportunity using two Korean cohorts: a hospital cohort from two centers and a national database. The impact of panel reactive antibody (PRA) based on the maximal PRA% and ABO on DDKT accessibility was analyzed using a competing risks regression model. In the hospital cohort (n = 4722), 88.2%, 8.7%, and 3.1% of patients belonged to 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-53157-2