Efficacy and safety of tofacitinib in rheumatoid arthritis: Nine years of real‐world data

Tofacitinib is a targeted JAK inhibitor used to treat rheumatoid arthritis. Despite some recent safety concerns, it is considered effective and safe with appropriate patient selection. Between May 2015 and May 2024, data were retrospectively analyzed from 112 patients with a diagnosis of RA in a ter...

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Veröffentlicht in:Clinical and translational science 2024-11, Vol.17 (11), p.e70084-n/a
Hauptverfasser: Ekin, Ali, Misirci, Salim, İldemir, Selin, Coskun, Belkıs Nihan, Yagiz, Burcu, Dalkilic, Ediz, Pehlivan, Yavuz
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Sprache:eng
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Zusammenfassung:Tofacitinib is a targeted JAK inhibitor used to treat rheumatoid arthritis. Despite some recent safety concerns, it is considered effective and safe with appropriate patient selection. Between May 2015 and May 2024, data were retrospectively analyzed from 112 patients with a diagnosis of RA in a tertiary care hospital who had received tofacitinib for at least 1 month, with or without prior biologic DMARDs. The mean disease duration was 12 years, and the median duration of tofacitinib use was 32.5 months. The p‐value for all disease activity parameters evaluated for effectiveness between the 1st‐ and 3rd‐month visits was
ISSN:1752-8054
1752-8062
1752-8062
DOI:10.1111/cts.70084