(E)-5-[Bromo(phenyl)methylene]-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole

(E)-5-[Bromo(phenyl)methylene]-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole

One-pot synthesis of (E)-5-[bromo(phenyl)methylene]-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole (9) from propargylic alcohol 5 and p-toluamide (6) was achieved via gold(III)-catalyzed propargylic substitution, followed by gold(III)-catalyzed bromocyclization. The structure of 9 was confirmed by an X-ray...

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Veröffentlicht in:MolBank 2024-03, Vol.2024 (1), p.M1769
Hauptverfasser: Morita, Nobuyoshi, Kurami, Saki, Ishii, Naho, Tanaka, Kosaku, Hashimoto, Yoshimitsu, Tamura, Osamu
Format: Artikel
Sprache:eng
Schlagworte:
Alcohol
bromocyclization
Chromatography
Crystal structure
Crystallography
Gold
gold catalyst
Methylene
propargylic substitution
Single crystals
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Zusammenfassung:One-pot synthesis of (E)-5-[bromo(phenyl)methylene]-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole (9) from propargylic alcohol 5 and p-toluamide (6) was achieved via gold(III)-catalyzed propargylic substitution, followed by gold(III)-catalyzed bromocyclization. The structure of 9 was confirmed by an X-ray crystallographic analysis.
ISSN:1422-8599
1422-8599
DOI:10.3390/M1769