Dexmedetomidine attenuates the positive chronotropic effects of intravenous atropine in patients with bradycardia during spinal anaesthesia: a retrospective study

Introduction Dexmedetomidine is a sedative used during spinal anaesthesia. However, it frequently induces bradycardia. Although intravenous atropine is often used for treating bradycardia during regional anaesthesia, the response to atropine might be attenuated by concomitantly administering sedativ...

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Veröffentlicht in:JA Clinical Reports 2018-09, Vol.4 (1), p.70-70, Article 70
Hauptverfasser: Fujii, Emi, Tanaka-Mizuno, Sachiko, Fujino, Kazunori, Fujii, Masashi, Furuno, Masae, Sugimoto, Yasushi, Takabuchi, Satoshi, Eguchi, Yutaka
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Sprache:eng
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Zusammenfassung:Introduction Dexmedetomidine is a sedative used during spinal anaesthesia. However, it frequently induces bradycardia. Although intravenous atropine is often used for treating bradycardia during regional anaesthesia, the response to atropine might be attenuated by concomitantly administering sedatives. Methods We examined the effects of atropine used for treating bradycardia during spinal anaesthesia among patients receiving dexmedetomidine (D group), propofol (P group), or neither (nonDnonP group) for sedation, retrospectively. Results A total of 108 patients were included. Heart rate was significantly slower at all time points in the D group ( n  = 69) than in the nonDnonP group ( n  = 14) ( p  
ISSN:2363-9024
2363-9024
DOI:10.1186/s40981-018-0207-9