Quantitative assessment of adherence to treatment in clinical medicine: protocol, procedure, interpretation

We developed and embedded in research and clinical practice of the method of quantitative evaluation of adherence to treatment in clinical medicine. Assessment of adherence is investigated by completion of the questionnaire. Analysis of the answers allows us to quantitatively calculate the indicators of adherence to drug therapy, medical support, modification of lifestyle and integral adherence to treatment. In accordance with the obtained results, an adherence can be «high,» «satisfactory» or «unsatisfactory», serving as a basis for making research or treatment decisions. Dynamic quantitative assessment of adherence allows to assess the current efficacy of interventions and to forecast their trends. The questionnaire is recommended for use in clinical practice when treating patients with chronic diseases, as well as at the stages of organization and execution of clinical studies and clinical trials.