Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017-2019

We sequenced 29 carbapenemase-producing Klebsiella pneumoniae isolates from a neonatal intensive care unit in Ghana. Twenty-eight isolates were sequence type 17 with bla and differed by 0-32 single-nucleotide polymorphisms. Improved surveillance and infection control are needed to characterize and c...

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Veröffentlicht in:	Emerging infectious diseases 2020-09, Vol.26 (9), p.2235-2238
Hauptverfasser:	Labi, Appiah-Korang, Nielsen, Karen L, Marvig, Rasmus L, Bjerrum, Stephanie, Enweronu-Laryea, Christabel, Bennedbæk, Marc, Newman, Mercy J, Ayibor, Prosper K, Andersen, Leif P, Kurtzhals, Jørgen A L
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibiotics Antimicrobial agents Bacteria Bacterial Proteins - genetics Beta lactamases beta-Lactamases - genetics bloodstream infection carbapenemase-producing Dispatch Drug resistance Epidemiology Evolution & development Genomes Ghana Ghana - epidemiology Gram-negative bacteria Health aspects Humans in Neonatal Intensive Care Unit, Ghana, 2017–2019 Infant, Newborn Infections Intensive care Intensive Care Units, Neonatal Klebsiella Infections - epidemiology Klebsiella pneumoniae Klebsiella pneumoniae - genetics Microbial drug resistance Microbial Sensitivity Tests Neonatal intensive care neonatal intensive care unit Newborn babies Newborn infants Oxacillinase-181 Carbapenemase-Producing Oxalic acid Plasmids Pneumonia Single nucleotide polymorphisms Teaching hospitals Tetracyclines whole-genome sequencing Working groups
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Zusammenfassung:	We sequenced 29 carbapenemase-producing Klebsiella pneumoniae isolates from a neonatal intensive care unit in Ghana. Twenty-eight isolates were sequence type 17 with bla and differed by 0-32 single-nucleotide polymorphisms. Improved surveillance and infection control are needed to characterize and curb the spread of multidrug-resistant organisms in sub-Saharan Africa.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2609.200562