The Genus Hyssopus: Traditional Use, Phytochemicals and Pharmacological Properties

According to modern concepts, the genus L. includes seven plant species ( (Trautv.) Iljin ex Prochorov. & Lebel; Boriss; C.Y.Wu & H.W. Li; Boriss.; L.; (Dubj.) Pazij; (Rech.f.) Rech.f.). The plants are rich in various groups of biologically active substances with a wide spectrum of pharmacological action. This review presents a modern comprehensive overview of the botanical research, extraction methods, chemical composition and pharmacological activity of plants of the genus L. As a result of the review, it was established that the chemical composition of plant extracts of the genus L. depends on various factors (place of growth, weather conditions, chemotypes, extraction methods, etc.). For the further use of the plants, the extraction methods and low-molecular metabolites isolated from them (mono- and sesquiterpenoids, flavonoids, alkaloids, etc.) are discussed. The data from the review provide an assessment of the relevance.