Exposure to Leishmania spp. infection and Lutzomyia spp. in individuals living in an area endemic for visceral leishmaniasis in Brazil

This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease. The presence of antibodies specific for Leishmania spp. and saliva of Lutzomyia spp. and that of L. infantum DNA in blood were evaluated. Antibodies against Leishmania spp. a...

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Veröffentlicht in:	Revista da Sociedade Brasileira de Medicina Tropical 2020-01, Vol.53, p.e20190320-e20190320
Hauptverfasser:	Hirata, Karina Yukie, Oliveira Sobrinho, Edenilson Borges de, Rigon, Lais, Utsunomiya, Yuri Tani, Tomokane, Thaise Yumie, Laurenti, Márcia Dalastra, Marcondes, Mary
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Animals Antibodies Brazil Enzyme-Linked Immunosorbent Assay Female Humans Humoral immunity Insect Vectors - parasitology Leishmania - genetics Leishmania - immunology Leishmania - isolation & purification Leishmaniasis, Visceral - epidemiology Leishmaniasis, Visceral - transmission Male Middle Aged Polymerase Chain Reaction Psychodidae - parasitology Sandfly saliva Serology Short Communication TROPICAL MEDICINE Young Adult
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Zusammenfassung:	This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease. The presence of antibodies specific for Leishmania spp. and saliva of Lutzomyia spp. and that of L. infantum DNA in blood were evaluated. Antibodies against Leishmania spp. and sandfly saliva were observed in 20.8% and 37.7% of individuals, respectively. DNA of Leishmania spp. was amplified from the blood of one patient. The results suggest that Leishmania spp. infection may be underdiagnosed in this area.
ISSN:	0037-8682 1678-9849 1678-9849
DOI:	10.1590/0037-8682-0320-2019