Exposure to fine particulate matter and temporal dynamics of episodic memory and depressive symptoms in older women

Exposure to fine particulate matter and temporal dynamics of episodic memory and depressive symptoms in older women

•Accelerated decline in episodic memory was associated with long-term PM2.5 exposure.•No significant direct association between PM2.5 and changes in depressive symptoms.•PM2.5 indirectly increased depressive symptoms via declines in episodic memory.•Findings were robust in women who remained cogniti...

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Veröffentlicht in:Environment international 2020-02, Vol.135, p.105196-105196, Article 105196
Hauptverfasser: Petkus, Andrew J., Younan, Diana, Widaman, Keith, Gatz, Margaret, Manson, JoAnn E., Wang, Xinhui, Serre, Marc, Vizuete, William, Chui, Helena, Espeland, Mark A., Resnick, Susan, Chen, Jiu-Chiuan
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Air Pollutants - toxicity
Depression
Depressive symptoms
Environmental Exposure
Episodic memory
Female
Humans
Longitudinal Studies
Memory, Episodic
Particulate matter
Particulate Matter - toxicity
Structural equation modeling
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Zusammenfassung:•Accelerated decline in episodic memory was associated with long-term PM2.5 exposure.•No significant direct association between PM2.5 and changes in depressive symptoms.•PM2.5 indirectly increased depressive symptoms via declines in episodic memory.•Findings were robust in women who remained cognitively-intact during the follow-up. Emerging data suggests PM2.5 (particulate matter with aerodynamic diameter
ISSN:0160-4120
1873-6750
DOI:10.1016/j.envint.2019.105196