Interaction of Left Ventricular Size and Sex on Outcome of Cardiac Resynchronization Therapy Among Patients With a Narrow QRS Duration in the EchoCRT Trial

Background Longer QRS duration (QRSd) improves, but increased left ventricular (LV) end‐diastolic volume (LVEDV) reduces, efficacy of cardiac resynchronization therapy (CRT). QRSd/LVEDV ratios differ between sexes. We hypothesized that in the EchoCRT (Echocardiography Guided Cardiac Resynchronizatio...

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Veröffentlicht in:	Journal of the American Heart Association 2018-06, Vol.7 (11), p.n/a
Hauptverfasser:	Varma, Niraj, Sogaard, Peter, Bax, Jeroen J., Abraham, William T., Borer, Jeffrey S., Dickstein, Kenneth, Singh, Jagmeet P., Gras, Daniel, Holzmeister, Johannes, Brugada, Josep, Ruschitzka, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Aged cardiac resynchronization therapy Cardiac Resynchronization Therapy - adverse effects Cardiac Resynchronization Therapy - mortality Echocardiography Electrocardiography Female Heart Conduction System - physiopathology Heart Failure - diagnosis Heart Failure - mortality Heart Failure - physiopathology Heart Failure - therapy Heart Rate Heart Ventricles - diagnostic imaging Heart Ventricles - physiopathology Humans Hypertrophy, Left Ventricular - diagnosis Hypertrophy, Left Ventricular - mortality Hypertrophy, Left Ventricular - physiopathology Hypertrophy, Left Ventricular - therapy left ventricle size Male Middle Aged narrow QRS Original Research Risk Assessment Risk Factors Sex Factors Time Factors Treatment Outcome Ventricular Function, Left Ventricular Remodeling
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Zusammenfassung:	Background Longer QRS duration (QRSd) improves, but increased left ventricular (LV) end‐diastolic volume (LVEDV) reduces, efficacy of cardiac resynchronization therapy (CRT). QRSd/LVEDV ratios differ between sexes. We hypothesized that in the EchoCRT (Echocardiography Guided Cardiac Resynchronization Therapy) trial enrolling patients with heart failure with QRSd
ISSN:	2047-9980 2047-9980
DOI:	10.1161/JAHA.118.009592