Papillary thyroid carcinoma presented as a hypercaptant nodule: a case report

Hot thyroid nodules are mostly benign and rarely show a malignant nature. Here we present the case of a 45-year-old man with a hypercaptant but ultrasound suspicious nodule; he underwent fine needle aspiration (FNA) and subsequent thyroidectomy. Pathology revealed a papillary thyroid carcinoma (PTC) with focal tall cell features, positivity to BRAF V600E and focal hyperspression of p53. A multidisciplinary clinicopathological approach is crucial for the correct diagnosis. •Hot nodules are considered rare entities.•To date, the true incidence of cancer within a hypercaptant nodule may be underestimated.•Cases of hot nodules with suspicious features require a multidisciplinary approach.