Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors

In this study, a cohort of 95 dogs diagnosed with mammary tumors underwent evaluation through multiple surgical techniques, alongside medication and ovariohysterectomy. The assessment included margin completeness to analyze clinical outcomes. Complete excision of the tumors has been shown to enhance survival time, extend disease-free intervals, and improve the overall well-being of the animals across different clinical stages. The findings suggest that complete surgical excision provides benefits, even in cases where lymphatic invasion is present. Radical mastectomy, which may disrupt potential lymphatic routes for tumor invasion and recurrence, demonstrated better clinical outcomes compared to conservative therapy. However, further investigations are necessary to validate these clinical results and address the side effects associated with radical mastectomy. Despite the possibility of postoperative complications, studies continue to advocate for more radical mastectomies due to their favorable risk-benefit ratio. Additionally, advancements in postoperative treatment can now effectively mitigate many of these complications. This study emphasizes the importance of radical mastectomy in treating malignant mammary tumors in dogs, providing insights that could lead to the development of more effective treatment strategies.