Comparative Transcriptome Analysis of the Pinewood Nematode Bursaphelenchus xylophilus Reveals the Molecular Mechanism Underlying Its Defense Response to Host-Derived α-pinene

is fatal to the pine trees around the world. The production of the pine tree secondary metabolite gradually increases in response to a infestation, via a stress reaction mechanism(s). α-pinene is needed to combat the early stages of infection and colonization, and to counter its pathogenesis. Therefore, research is needed to characterize the underlying molecular response(s) of to resist α-pinene. We examined the effects of different concentrations of α-pinene on the mortality and reproduction rate of in vitro. The molecular response by which resists α-pinene was examined via comparative transcriptomics of the nematode. Notably, genes involved in detoxification, transport, and receptor activities were differentially expressed in response to two different concentrations of α-pinene compared with control. Our results contribute to our understanding of the molecular mechanisms by which responds to monoterpenes in general, and the pathogenesis of .