Prevalence of drug-resistant tuberculosis in Zimbabwe: A health facility-based cross-sectional survey

•The prevalence of RR-TB was [4.0% (95% CI, 2.9, 5.4%) and 14.2% (95% CI, 8.9, 21.1%)] among new and retreatment patients, respectively.•The prevalence of MDR-TB was 2.0% (95% CI, 1.3, 3.1%) and 6.4% (95% CI, 2.4, 10.3%) among new and retreatment TB patients, respectively.•Weighted prevalence of RR-...

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Veröffentlicht in:	International journal of infectious diseases 2019-10, Vol.87, p.119-125
Hauptverfasser:	Timire, Collins, Metcalfe, John Z., Chirenda, Joconiah, Scholten, Jerod N., Manyame-Murwira, Barbara, Ngwenya, Mkhokheli, Matambo, Ronnie, Charambira, Kelvin, Mutunzi, Herbert, Kalisvaart, Nico, Sandy, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anti-Bacterial Agents - pharmacology Child Cross-Sectional Studies Drug Resistance, Bacterial Drug resistant TB Female Gene Xpert Health Facilities Humans Isoniazid - pharmacology Male MDR Microbial Sensitivity Tests Middle Aged Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Prevalence Previously treated TB Rifampicin resistant TB Rifampin - pharmacology Risk Factors Sensitivity and Specificity Sputum - microbiology Surveys and Questionnaires Tuberculosis, Multidrug-Resistant - epidemiology Tuberculosis, Multidrug-Resistant - microbiology Young Adult Zimbabwe Zimbabwe - epidemiology
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Zusammenfassung:	•The prevalence of RR-TB was [4.0% (95% CI, 2.9, 5.4%) and 14.2% (95% CI, 8.9, 21.1%)] among new and retreatment patients, respectively.•The prevalence of MDR-TB was 2.0% (95% CI, 1.3, 3.1%) and 6.4% (95% CI, 2.4, 10.3%) among new and retreatment TB patients, respectively.•Weighted prevalence of RR-TB and MDR-TB among new TB patients were 4.6% (95% CI, 3.0, 6.2%) and 1.8% (95% CI, 1.0, 2.5%), respectively.•Risk factors for RR-TB included prior TB treatment, self-reported HIV infection, travel outside Zimbabwe for >one month (univariate), and age
ISSN:	1201-9712 1878-3511
DOI:	10.1016/j.ijid.2019.07.021