Duration of viral shedding in asymptomatic or mild cases of novel coronavirus disease 2019 (COVID-19) from a cruise ship: A single-hospital experience in Tokyo, Japan

•We reported our experience of the course of PCR assays and the duration of viral shedding in 23 asymptomatic or mild COVID-19 patients from the cruise ship.•The median duration of viral shedding was 19 days (range, 6–37 days) from initial viral detection.•Eight of the 23 cases (35%) had another pos...

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Veröffentlicht in:International journal of infectious diseases 2020-08, Vol.97, p.293-295
Hauptverfasser: Miyamae, Yuka, Hayashi, Toshiya, Yonezawa, Hitoshi, Fujihara, Jin, Matsumoto, Yousuke, Ito, Takafumi, Tsubota, Takaya, Ishii, Koji
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Sprache:eng
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Zusammenfassung:•We reported our experience of the course of PCR assays and the duration of viral shedding in 23 asymptomatic or mild COVID-19 patients from the cruise ship.•The median duration of viral shedding was 19 days (range, 6–37 days) from initial viral detection.•Eight of the 23 cases (35%) had another positive PCR result after testing negative once. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of novel coronavirus disease 2019 (COVID-19), was first reported in Wuhan, China, and now has spread across the world as a global pandemic. The propagation from asymptomatic polymerase chain reaction (PCR)-positive individuals represents a complicating factor in the efforts to control the COVID-19 pandemic. We examined the course of PCR assays and the duration of viral shedding in 23 asymptomatic or mild COVID-19 patients from the cruise ship who were admitted to our hospital. Among these 23 cases, the median duration of viral shedding was 19 days (range, 6–37 days) from initial viral detection. Eight cases (35%) had another positive PCR result after testing negative once. Although the duration of viral shedding was approximately three weeks, the infectivity and transmissibility period from asymptomatic and mild COVID-19 cases is unclear. Further studies are needed to determine how long such asymptomatic and mild COVID-19 cases have infectivity.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2020.06.020