Congenital factor VII deficiency: Multidisciplinary approach is the key to successful perioperative outcome

Pre-operative laboratory test showed elevated prothrombin time (PT)/international normalized ratio (INR) (PT-39.6 s/INR-3.4) with normal activated partial thromboplastin time (aPTT), liver enzymes and platelet count. [5] Other treatment alternatives include FFP and prothrombin complex concentrate containing factors II, VII, IX and X.[2] Successful perioperative management of an infant with FVII deficiency necessitates timely administration of rFVIIa with PT/INR monitoring.