Efficacy and Safety of Oral Administration of a Mixture of Probiotic Strains in Patients with Psoriasis: A Randomized Controlled Clinical Trial

The aim of this 12-week randomized, double-blind, placebo-controlled trial was to determine the efficacy and safety of a probiotic mixture in the reduction of psoriasis severity. Ninety 18-70-year-old adults with plaque psoriasis were randomized into probiotic and placebo groups. At 12-week follow-u...

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Veröffentlicht in:Acta dermato-venereologica 2019-11, Vol.99 (12), p.1078-1084
Hauptverfasser: Navarro-López, Vicente, Martínez-Andrés, Asunción, Ramírez-Boscá, Ana, Ruzafa-Costas, Beatriz, Núñez-Delegido, Eva, Carrión-Gutiérrez, Miguel A, Prieto-Merino, David, Codoñer-Cortés, Francisco, Ramón-Vidal, Daniel, Genovés-Martínez, Salvador, Chenoll-Cuadros, Empar, Pérez-Orquín, José M, Picó-Monllor, José A, Chumillas-Lidón, Sara
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Sprache:eng
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Zusammenfassung:The aim of this 12-week randomized, double-blind, placebo-controlled trial was to determine the efficacy and safety of a probiotic mixture in the reduction of psoriasis severity. Ninety 18-70-year-old adults with plaque psoriasis were randomized into probiotic and placebo groups. At 12-week follow-up, 66.7% of patients in the probiotic group and 41.9% in the placebo group showed a reduction in Psoriasis Area and Severity Index of up to 75% (p 
ISSN:0001-5555
1651-2057
DOI:10.2340/00015555-3305