Magnetic nanoparticle-catalysed synthesis of quinoline derivatives: A green and sustainable method

Greener and sustainable synthetic strategies have been evolving as the demanding domain of organic synthesis during the last decade. Green synthesis involves the development of method that decrease or eliminate the use of hazardous chemicals, and make use of renewable or recyclable resources. By incorporating the fundamentals and methodologies of green synthesis, organic chemists have the ability to develop valuable organic molecular frameworks which also demonstrate a strong commitment to environmental sustainability. In this context, the nanoparticle has garnered significant interest due to its various features, adhering to the principles of green synthesis. Specifically, magnetic nanoparticles have been trending extensive uses in green synthesis throughout the past decade. The role of magnetic nanoparticle has an irreplaceable place in the synthesis of biologically valuable frameworks named as quinoline. Quinoline are considered a privileged structure among organic compounds and offer a promising avenue for identifying lead structures in the search of new synthetic molecules (Saquinavir, Imiquimod and Reabamipide) having potential medicinal values and other important prospects. So, it’s always indeed to the organic and medicinal chemist to develop biologically active frameworks by the green synthesis. The current manuscript consolidates the existing research on properties of environment-friendly magnetic nanoparticles for generating an extended range of valuable quinoline derivatives. [Display omitted]