Multidrug-resistant pandemic (H1N1) 2009 infection in immunocompetent child

Recent case reports describe multidrug-resistant influenza A pandemic (H1N1) 2009 virus infection in immunocompromised patients exposed to neuraminidase inhibitors because of an I223R neuraminidase mutation. We report a case of multidrug-resistant pandemic (H1N1) 2009 bearing the I223R mutation in a...

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Veröffentlicht in:	Emerging infectious diseases 2011-08, Vol.17 (8), p.1472-1474
Hauptverfasser:	Eshaghi, AliReza, Patel, Samir N, Sarabia, Alicia, Higgins, Rachel R, Savchenko, Alexei, Stojios, Peter J, Li, Yan, Bastien, Nathalie, Alexander, David C, Low, Donald E, Gubbay, Jonathan B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antiviral agents Antiviral Agents - pharmacology Dispatch Drug resistance in microorganisms Drug Resistance, Multiple, Viral - genetics drug resistant Enzyme Inhibitors - pharmacology Epidemics Female H1N1 Health aspects Humans Immunocompetence Influenza influenza A Influenza A Virus, H1N1 Subtype - drug effects Influenza A Virus, H1N1 Subtype - enzymology Influenza A Virus, H1N1 Subtype - genetics Influenza A Virus, H1N1 Subtype - isolation & purification Influenza viruses Influenza, Human - drug therapy Influenza, Human - virology Mutation Neuraminidase - genetics Ontario oseltamivir Oseltamivir - pharmacology pandemic Pandemics viruses Zanamivir - pharmacology
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Zusammenfassung:	Recent case reports describe multidrug-resistant influenza A pandemic (H1N1) 2009 virus infection in immunocompromised patients exposed to neuraminidase inhibitors because of an I223R neuraminidase mutation. We report a case of multidrug-resistant pandemic (H1N1) 2009 bearing the I223R mutation in an ambulatory child with no previous exposure to neuraminidase inhibitors.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1708.102004