Application of Lie Symmetry to a Mathematical Model that Describes a Cancer Sub-Network

In this paper, a mathematical model of a cancer sub-network is analysed from the view point of Lie symmetry methods. This model discusses a human cancer cell which is developed due to the dysfunction of some genes at the R-checkpoint during the cell cycle. The primary purpose of this paper is to app...

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Veröffentlicht in:Symmetry (Basel) 2022-02, Vol.14 (2), p.400
1. Verfasser: Matadi, Maba Boniface
Format: Artikel
Sprache:eng
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Zusammenfassung:In this paper, a mathematical model of a cancer sub-network is analysed from the view point of Lie symmetry methods. This model discusses a human cancer cell which is developed due to the dysfunction of some genes at the R-checkpoint during the cell cycle. The primary purpose of this paper is to apply the techniques of Lie symmetry to the model and present some approximated solutions for the three-dimensional system of first-order ordinary differential equations describing a cancer sub-network. The result shows that the phosphatase gene (Cdc25A) regulates the cyclin-dependent kinases inhibitor (P27Kip1). Furthermore, this research discovered that the activity that reverses the inhibitory effects on cell cycle progression at the R-checkpoint initiates a pathway.
ISSN:2073-8994
2073-8994
DOI:10.3390/sym14020400