The History and Future of Basic and Translational Cell-Free DNA Research at a Glance

The History and Future of Basic and Translational Cell-Free DNA Research at a Glance

We discuss the early history of the structure of DNA and its involvement in gene structure as well as its mobility in and between cells and between tissues in the form of circulating cell-free DNA (cfDNA). This is followed by a view of the present status of the studies on cfDNA and clinical applicat...

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Veröffentlicht in:Diagnostics (Basel) 2022-05, Vol.12 (5), p.1192
Hauptverfasser: Gahan, Peter B, Schwarzenbach, Heidi, Anker, Philippe
Format: Artikel
Sprache:eng
Schlagworte:
Animal feathers
Animals
Blood transfusions
cancer
Cell cycle
clinical medicine
DNA
Experiments
Genes
Genetic engineering
history
methodology
Microscopy
Review
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Beschreibung
Zusammenfassung:We discuss the early history of the structure of DNA and its involvement in gene structure as well as its mobility in and between cells and between tissues in the form of circulating cell-free DNA (cfDNA). This is followed by a view of the present status of the studies on cfDNA and clinical applications of circulating cell-free tumor DNA (ctDNA). The future developments and roles of ctDNA are also considered.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics12051192