Human challenge pilot study with Cyclospora cayetanensis

We describe a pilot study that attempted to infect human volunteers with Cyclospora cayetanensis. Seven healthy volunteers ingested an inoculum of Cyclospora oocysts (approximately 200-49,000 oocysts). The volunteers did not experience symptoms of gastroenteritis, and no oocysts were detected in any...

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Veröffentlicht in:	Emerging infectious diseases 2004-04, Vol.10 (4), p.726-728
Hauptverfasser:	Alfano-Sobsey, Edith M, Eberhard, Mark L, Seed, John R, Weber, David J, Won, Kimberly Y, Nace, Eva K, Moe, Christine L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Cyclospora - isolation & purification Cyclospora cayetanensis Cyclosporiasis - etiology Cyclosporine Dispatch Feces - parasitology Haiti Human challenge study Humans Infectivity Middle Aged Oocysts - isolation & purification Pilot Projects United States
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Beschreibung
Zusammenfassung:	We describe a pilot study that attempted to infect human volunteers with Cyclospora cayetanensis. Seven healthy volunteers ingested an inoculum of Cyclospora oocysts (approximately 200-49,000 oocysts). The volunteers did not experience symptoms of gastroenteritis, and no oocysts were detected in any stool samples during the 16 weeks volunteers were monitored.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1004.030356