Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?

Surgical treatment of hyperparathyroidism related to chronic kidney disease is a real challenge for Brazilian public health care. High cost medications and long waiting lines to perform preoperative exams, especially technetium Tc 99m Sestamibi (MIBI) are some of the reasons. Despite the reality tha...

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Veröffentlicht in:Brazilian journal of otorhinolaryngology 2022-09, Vol.88 (5), p.740-744
Hauptverfasser: Neves, Murilo Catafesta das, Abrahão, Augusto Riedel, Abrahão, Marcio, Rosano, Marcello, Rocha, Lillian Andrade da, Machado, Hanna Karla Andrade Guapyassu, Santos, Rodrigo Oliveira
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Sprache:eng
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Zusammenfassung:Surgical treatment of hyperparathyroidism related to chronic kidney disease is a real challenge for Brazilian public health care. High cost medications and long waiting lines to perform preoperative exams, especially technetium Tc 99m Sestamibi (MIBI) are some of the reasons. Despite the reality that the aid of localization exams are questionable in this scenario, doctors are too apprehensive in performing surgery without it. The study aimed at evaluating the efficacy of surgery for renal hyperparathyroidism without preoperative MIBI. A total of 114 patients were surgically treated. Total parathyroidectomy with autotransplantation and subtotal parathyroidectomy were carried out without preoperative MIBI. Among the 114 patients undergoing surgery, 37 had secondary hyperparathyroidism in dialysis replacement, and 77 patients had post-renal transplant persistent disease. We were successful in 107 cases with only 7 failures (93.8% of success rate). Among these failures, only one parathyroid gland was not found in 4 cases, 2 parathyroid glands were not found in 2 cases and in 1 patient the 4 glands were found but this patient remained hypercalcemic and a postoperative diagnosis of supernumerary parathyroid gland was made. Surgery for treatment of renal hyperparathyroidism proved to be an effective (93.8%) and reproductible procedure, even without MIBI. O tratamento cirúrgico do hiperparatireoidismo relacionado à doença renal crônica é um verdadeiro desafio para a saúde pública brasileira. Medicamentos de alto custo e longas filas de espera para a realização de exames pré-operatórios, principalmente a cintilografia com tecnécio Tc-99m Sestamibi (MIBI) são alguns dos motivos. Apesar da contribuição de exames de localização ser questionável neste cenário, os médicos ficam muito apreensivos em realizar uma cirurgia sem ele. O estudo teve como objetivo avaliar a eficácia da cirurgia para hiperparatireoidismo renal sem a realização de MIBI pré-operatório. Um total de 114 pacientes foram tratados cirurgicamente. A paratireoidectomia total com autotransplante e a paratireoidectomia subtotal foram realizadas sem MIBI pré-operatório. Entre os 114 pacientes submetidos à cirurgia, 37 apresentavam hiperparatireoidismo secundário em reposição dialítica e 77 pacientes apresentavam doença persistente pós-transplante renal. Tivemos sucesso em 107 casos, com apenas 7 falhas (93,8% de taxa de sucesso). Dentre essas falhas, uma glândula paratireoide não foi encontrada em 4 casos,
ISSN:1808-8694
1808-8686
1808-8686
DOI:10.1016/j.bjorl.2020.10.009