Use of topical povidone-iodine resulting in a iododerma

In our literature survey, we came across a case presentation related to iododerma after topical iodine application; it was reported that it occurred after anal fissure. Another instance that we came across in our literature survey was that of a case which developed acute kidney failure and respiratory insufficiency with skin lesions in the shape of vegetative mass and vesicular lesions that developed after cardiac catheter application with iodized contrast substance, in addition to systemic findings. Toxicity is reported in areas rich in sebaceous glands, in which there is more absorption, especially after topical application, in cases where skin integrity is compromised.