High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma

High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma

Glioblastoma (GBM) is the most common primary brain malignancy in adults. Despite multimodal treatment that involves maximal safe resection, concurrent chemoradiotherapy, and tumour treatment for supratentorial lesions, the prognosis remains poor. The current median overall survival is only

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Veröffentlicht in:International journal of molecular sciences 2023-09, Vol.24 (17), p.13367
Hauptverfasser: Chen, Ying-Tso, Chung, Chia-Li, Cheng, Yu-Wen, Lin, Chien-Ju, Tseng, Tzu-Ting, Hsu, Shu-Shong, Tsai, Hung-Pei, Kwan, Aij-Lie
Format: Artikel
Sprache:eng
Schlagworte:
Apoptosis
Brain cancer
Brain tumors
Cell cycle
Development and progression
GBM
Glioma
Gliomas
Medical prognosis
Pathogenesis
Prognosis
Protein binding
Proteins
Surgery
Thioredoxin
TMZ-sensitivity
TXNDC11
Wound healing
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Zusammenfassung:Glioblastoma (GBM) is the most common primary brain malignancy in adults. Despite multimodal treatment that involves maximal safe resection, concurrent chemoradiotherapy, and tumour treatment for supratentorial lesions, the prognosis remains poor. The current median overall survival is only
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms241713367