Advanced fructo-oligosaccharides improve itching and aberrant epidermal lipid composition in children with atopic dermatitis

The effects of fructo-oligosaccharides (FOS) on atopic dermatitis (AD) have not been determined. In a randomized, double-blind, placebo-controlled trial, children with AD aged 24 months to 17 years received either advanced FOS containing 4.25 g of 1-kestose or a placebo (maltose) for 12 weeks. The S...

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Veröffentlicht in:	Frontiers in microbiology 2024-04, Vol.15, p.1383779-1383779
Hauptverfasser:	Kim, Sukyung, Kang, Bae-Gon, Sa, Soonok, Park, Se Young, Ryu, Kyungheon, Lee, Jinyoung, Park, Boram, Kwon, Mijeong, Kim, Yeonghee, Kim, Jiwon, Shin, Sanghee, Jang, Sehun, Kim, Byung Eui, Bae, Jaewoong, Ahn, Kangmo, Liu, Kwang-Hyeon, Kim, Jihyun
Format:	Artikel
Sprache:	eng
Schlagworte:	atopic dermatitis fatty acid elongase fructo-oligosaccharides kestose Microbiology prebiotics
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Beschreibung
Zusammenfassung:	The effects of fructo-oligosaccharides (FOS) on atopic dermatitis (AD) have not been determined. In a randomized, double-blind, placebo-controlled trial, children with AD aged 24 months to 17 years received either advanced FOS containing 4.25 g of 1-kestose or a placebo (maltose) for 12 weeks. The SCORAD and itching scores were reduced in patients treated with both FOS (all
ISSN:	1664-302X 1664-302X
DOI:	10.3389/fmicb.2024.1383779