Quality of anticoagulant therapy and the incidence of in‐stent thrombosis after venous stenting

In patients with a venous outflow obstruction following iliofemoral deep vein thrombosis stenting of the venous tract to prevent or alleviate postthrombotic syndrome is applied with increasing frequency. The impact of the quality of anticoagulant therapy with vitamin K antagonists (VKAs) on the deve...

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Veröffentlicht in:Research and practice in thrombosis and haemostasis 2020-05, Vol.4 (4), p.594-603
Hauptverfasser: Notten, Pascale, van Laanen, Jorinde H.H., Eijgenraam, Pieter, de Wolf, Mark A.F., Kurstjens, Ralph L.M., ten Cate, Hugo, ten Cate‐Hoek, Arina J.
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Sprache:eng
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Zusammenfassung:In patients with a venous outflow obstruction following iliofemoral deep vein thrombosis stenting of the venous tract to prevent or alleviate postthrombotic syndrome is applied with increasing frequency. The impact of the quality of anticoagulant therapy with vitamin K antagonists (VKAs) on the development of in‐stent thrombosis is currently unknown. To determine the association between the quality of postinterventional VKA treatment and the occurrence of in‐stent thrombosis. Seventy‐nine patients with iliofemoral and/or caval venous stent placement for obstruction of the venous outflow were included in this study. All patients received postinterventional VKA. The quality of VKA anticoagulant therapy was expressed as the time within therapeutic range (TTR) calculated using the linear interpolation method and as the proportion of International Normalized Ratio (INR) values 
ISSN:2475-0379
2475-0379
DOI:10.1002/rth2.12330