New secoiridoid glycosides from the roots of Picrorhiza scrophulariiflora

New secoiridoid glycosides from the roots of Picrorhiza scrophulariiflora

Three new secoiridoid glycosides, named picrogentiosides A (1), B (2) and C (3), have been isolated from the underground parts of Picrorhiza Scrophulariiflora, together with the two known compounds plantamajoside (4) and plantainoside D (5). Their structures were established by spectroscopic analyse...

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2008-09, Vol.13 (9), p.2049-2057
Hauptverfasser: Zou, Lian-Chun, Zhu, Tong-Fei, Xiang, Hua, Yu, Lu, Yan, Zhi-Hui, Gan, Shu-Cai, Wang, Da-Cheng, Zeng, Sheng, Deng, Xu-Ming
Format: Artikel
Sprache:eng
Schlagworte:
B and C
Glycosides - chemistry
Glycosides - isolation & purification
Immunoenhancement
Iridoids - chemistry
Iridoids - isolation & purification
Molecular Structure
Picrogentiosides A
Picrorhiza - chemistry
Picrorhiza scrophulariiflora
Plant Extracts - chemistry
Plant Roots - chemistry
Secoiridoid glycosides
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Zusammenfassung:Three new secoiridoid glycosides, named picrogentiosides A (1), B (2) and C (3), have been isolated from the underground parts of Picrorhiza Scrophulariiflora, together with the two known compounds plantamajoside (4) and plantainoside D (5). Their structures were established by spectroscopic analyses and comparisons with data from related compounds. A pilot pharmacological study showed that picrogentiosides A (1) and B (2) have an immunomodulatory effect in vitro.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules13092049