Voluntary warnings and the limits of good prescribing behavior: the case for de-adoption of meperidine

Voluntary warnings and the limits of good prescribing behavior: the case for de-adoption of meperidine

Meperidine (pethidine) offers little to no therapeutic advantage over other opioids, may be more prone to abuse, and produces a neurotoxic metabolite with a long half-life. The Institute for Safe Medication Practices (ISMP) issued warnings in 2004 and 2005 suggesting that meperidine be avoided, and...

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Veröffentlicht in:Journal of pain research 2015-01, Vol.8 (Issue 1), p.879-884
Hauptverfasser: Friesen, Kevin J, Falk, Jamie, Bugden, Shawn
Format: Artikel
Sprache:eng
Schlagworte:
Addictions
Analgesics
Analysis
Central nervous system depressants
Delirium
Dosage and administration
Drug dosages
Drug stores
Medical research
Meperidine
Narcotics
Original Research
Pethidine
Pharmacy
Population
Prescription writing
Prescriptions
Regression analysis
Safety
Studies
Time series
Trends
Utilization
Warnings
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Beschreibung
Zusammenfassung:Meperidine (pethidine) offers little to no therapeutic advantage over other opioids, may be more prone to abuse, and produces a neurotoxic metabolite with a long half-life. The Institute for Safe Medication Practices (ISMP) issued warnings in 2004 and 2005 suggesting that meperidine be avoided, and when used, it should be in limited doses (
ISSN:1178-7090
1178-7090
DOI:10.2147/JPR.S96625